Non-Invasive Prenatal Test

What is NIPT?

NIPT (Non-Invasive Prenatal Testing) is a prenatal screening. During the screening, the DNA from the mother and foetus is extracted from a maternal blood sample and screened for the increased chance for specific chromosome problems.

What is fetal DNA or cffDNA?

Cell-free fetal DNA (cffDNA) is fetal DNA which circulates freely in the maternal blood. They are significantly smaller than maternal DNA fragments. The difference in size allows cffDNA to be distinguished from maternal DNA fragments.

Who should do NIPT?

NIPT is considered most appropriate for women who are at higher risk for having a baby with chromosomal abnormalities. These include women who have already had a baby with a chromosomal abnormality, those with abnormal results from a pregnancy ultrasound, those who have a family history of chromosomal abnormalities (such as the birth of a previpously affected child)  and those who will be age 35 or older when their baby is born.

Why is NIPT done?

The purpose of non-invasive prenatal testing is to screen for some of the most common chromosome anomalies, such as:

• Trisomy 21(Down syndrome)
• Trisomy 13 (Patau syndrome)and
• Trisomy 18 (Edwards syndrome)

This screening can also provide information about fetal sex and rhesus (Rh) blood type.

When is NIPT done?

NIPT test can be done any time after the 08th week of gestation. However, the optimal time is between the 11th and 13th weeks, and the procedure is typically performed between weeks 10–22. Sometimes an abnormality is seen during an 18- or 20-week ultrasound, in which case the next step is to draw blood for the NIPT.

AVAILABLE NIPT TEST OPTIONS AT BIOSYTECH:

NON-INVASIVE PRENATAL TEST (NIPT23)

What is NIPT 23?

NIPT 23 tests the chromosome anomalies of  23 pairs of chromosomes and fetal sex and rhesus (Rh) blood type. Sample Volume: 10 mL peripheral blood

NON-INVASIVE PRENATAL TEST (NIPT23+)

What is NIPT 23+?

NIPT 23+ tests not only the chromosome anomalies of 23 pairs of chromosomes but also 20 micro deletions and 20 micro duplications defects. Sample Volume: 10 mL peripheral blood

HARMONY PRENATAL TEST

What is Harmony test?

Harmony tests the chromosome anomalies (Trisomy 21, 13 and 18) and fetal sex and rhesus (Rh) blood type. Sample Volume: 20 mL peripheral blood

PANORAMA PRENATAL TEST

What is PANORAMA test?

PANORAMA tests not only the chromosome anomalies (Trisomy 21, 13 and 18) but also 05 micro deletions, 04 sex chromosome (X/Y) abnormalities (sex chromosome duplication) and Triploidy (69 set of chromosomes). Sample Volume: 20 mL peripheral blood.

Note: Special sample collection kit available for all the nipt tests.